Different biological models are used at PKDERM :

• Skin models (2D culture of keratinocytes, fibroblasts, melanocytes, etc.), 3D skin equivalent models, and human skin explants)

• Liver models (hepatocytes in 2D and 3D culture)

• 2D and 3D respiratory models (Calu-3, EpiAirway, PCLS…)

With more than 20 years of experience in pharmaceutical industry, PKDERM offers a wide range of innovative in vitro tests :

• Example of in vitro toxicology tests: dermal absorption, skin and eye irritation, sensitization, cytotoxicity, phototoxicity, endocrin

Consulting and analysis

Toxicological risk assessment

Through its consulting branch, Lifescientisoffers support in the toxicological assessment strategy and risk management, based on expertise in general toxicology and specialisation in both endocrine disruption and nanotechnologies.

Research and development

Development of encapsulation solutions.

Trough its biotechnology branch, Life scientis is co-developing with its customers solutions for microencapsulation and targeted release of compounds.

Phenocell offers Contract Research Organisation (CRO) services for in vitro studies in cosmetics and pharmacology :

• skin cells (melanocytes, sebocytes, keratinocytes, sensory neurons)